The best acne cream you would probably buy in this little planet of ours would probably contain the following contents – Benzoyl peroxide (which reduces acne and removing dead cells from the skin), Combination of Alcohol and Acetone, Resorcinol (controls small acne lesions), Salicylic acid (helps correct abnormal skin shedding) and sometimes in combination with Sulfur. Don’t worry as most of the over the counter products are tested extensively. But you should consult your dermatologist before you use them.